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Diana Mitchell

Diana Mitchell

Assistant Professor

Office

Life Sciences South 164A

Phone

208-885-0305

Mailing Address

Dept. of Biological Sciences
University of Idaho
875 Perimeter MS 3051
Moscow, Idaho 83844-3051

Research: Cellular & Molecular Biology

My current research interests involve immune cell function in the central nervous system, specifically the retina. I am particularly interested in microglia, which are resident innate immune cells of the central nervous system. Current efforts employ the zebrafish model system and seek to understand the role of microglia in the development of the retina, how microglia respond to neuronal cell death, and how they may support or be detrimental to neuronal regeneration.

I also contribute to research efforts in Dr. Deborah Stenkamp’s lab, where we are investigating mechanisms of photoreceptor fate decisions in the developing retina.

My current research interests involve immune cell function in the central nervous system, specifically the retina. I am particularly interested in microglia, which are resident innate immune cells of the central nervous system. Current efforts employ the zebrafish model system and seek to understand the role of microglia in the development of the retina, how microglia respond to neuronal cell death, and how they may support or be detrimental to neuronal regeneration.

I also contribute to research efforts in Dr. Deborah Stenkamp’s lab, where we are investigating mechanisms of photoreceptor fate decisions in the developing retina.

  • Chen B*, Legant WR*, Wang K, Shao L, Milkie DE, Davidson MW, Janetopoulos C, Wu XS, Hammer III JA, Liu Z, English BP, Mimori-Kiyosue Y, Romero DP, Ritter AT, Lippincott-Schwartz J, Fritz-Laylin L, Mullins RD, Mitchell DM, Bembenek JN, Reymann A-C, Bohme R, Grill SW, Wang JT, Seydoux G, Tulu US, Kiehart DP, Betzig E. (In Press). Lattice Light-Sheet Microscopy: Imaging Molecules to Embryos at High Spatiotemporal Resolution. Science.
  • Mitchell, DM, Uehlein-Klebanow LR, Bembenek JN. 2014 Protease-Dead Separase is Dominant Negative in the C. elegans Embryo. PLoS One, 9(9): e108188.
  • Mitchell, DM and Williams, MA. 2013. Disparate roles for STAT5 in primary and secondary CTL responses. Journal of Immunology, 190: 3390-3398.
  • Jay, DC, Mitchell, DM, and Williams, MA. 2013. Bim mediates the elimination of functionally unfit Th1 responders from the memory pool. PLoS One, 8(6): e67363.
  • Mitchell, DM, Ravkov, ER, and Williams, MA. 2010. Distinct roles for IL-2 and IL-15 in the differentiation and survival of CD8+ Effector and Memory T cells. Journal of Immunology, 184: 6719-6730.
  • Mitchell, DM and MA Williams. 2010. An Activation Marker Finds a Function. Immunity, 32: 9-11.

Contact

Department of Biological Sciences

Physical Address:
Life Sciences South 252

Mailing Address:
875 Perimeter Drive MS 3051
Moscow, ID 83844-3051

Phone: 208-885-6280

Fax: 208-885-7905

Email: biosci@uidaho.edu

Web: Department of Biological Sciences